Summit Behavioral Health
2115 County Road D East, Suite C-100
Maplewood,  MN 55109
Phone: 651-358-7020
Fax: 651-846-9890
Hours of operation
Tuesday through Saturday
9AM - 6PM

Major Depression Treatment

Treatment Resistant Depression is commonly defined as a failure of treatment to produce response or remission for patients after two or more attempts of adequate dose and duration. Depression is often difficult to treat, and many patients report that none of the treatments or psychotherapy interventions work over long period of time. Up to a third of patients don’t experience any improvement of symptoms and this is referred to as Treatment-Resistant Depression.

 Esketamine Intranasal spray is a new FDA approved treatment for severe depression and can result in rapid improvement of symptoms as opposed to oral antidepressants that can take weeks to start working. Summit Behavioral Health providers have the knowledge and expertise to determine if this new treatment can help patients achieve sustainable recovery. Call  6513587020 to know more about this new treatment option to treat resistant depression and to schedule an appointment. We accept most major insurances and are currently accepting new patients. We are able to accommodate new patient appointments within 3-7 days.

Symptoms Of Depression

  •     Feeling sad or having a depressed mood

  •     Loss of interest or pleasure in activities once enjoyed

  •     Changes in appetite — weight loss or gain unrelated to dieting

  •     Trouble sleeping or sleeping too much

  •     Loss of energy or increased fatigue

  •     Increase in purposeless physical activity (e.g., hand-wringing or pacing) or slowed movements & speech 

  •     Feeling worthless or guilty

  •     Difficulty thinking, concentrating or making decisions

  •     Thoughts of death or suicide


Symptoms must last at least two weeks for a diagnosis of depression.

Esketamine is FDA approved treatment that is self-administered by patients under the supervision of a healthcare provider in doctor’s office. Provider will monitor patients for 2 hours after administering Esketamine and  will determine when patients can leave. Also, patients are required to avoid driving or operating heavy equipment for 24 hours after taking this treatment.


Reimbursement / cost of treatment

Health insurances are starting to reimburse for Esketamine treatment but coverage varies based on your individual plan. Summit Behavioral health will work with your insurance company to determine coverage and obtain any prior-authorizations before starting the treatment. Call us to get the process started so we can get you the treatment needed in a timely manner.


Clinical Research & Evidence

According to the U.S. Food & Drug Administration website - The efficacy of Esketamine was evaluated in three short-term (four-week) clinical trials and one longer-term maintenance-of-effect trial. In the three short-term studies, patients were randomized to receive Esketamine or a placebo nasal spray. In light of the serious nature of treatment-resistant depression and the need for patients to receive some form of treatment, all patients in these studies started a new oral antidepressant at the time of randomization and the new antidepressant was continued throughout the trials. The primary efficacy measure was the change from baseline on a scale used to assess the severity of depressive symptoms. In one of the short-term studies, Esketamine nasal spray demonstrated statistically significant effect compared to placebo on the severity of depression, and some effect was seen within two days. The two other short-term trials did not meet the pre-specified statistical tests for demonstrating effectiveness. In the longer-term maintenance-of-effect trial, patients in stable remission or with stable response who continued treatment with Esketamine plus an other oral meds experienced a statistically significantly longer time to relapse of depressive symptoms than patients on placebo nasal spray plus an oral meds.

Other treatment options that are effective when administered concurrently are Psychotherapy, other oral meds or both. Talk to Summit Behavioral Health providers about your treatment options that are unique to your situation.



Connect with us today to know more about this new treatment option, insurance coverage and prior authorization process to get approval for treatment administration..

We accept most major insurances including Medicare, Medicaid, Minnesota Care, BCBS and more. We are  accepting new patients and you can be seen by our provider within 3-5 days. Call 651-358-7020 to book appointment or use our                                           to schedule at your convenience.

Would you like our specialists to call you to discuss esKetamine treatment?